Lab-in-a-tube: Detection of individual mouse cells for analysis in flexible split-wall microtube resonator sensors
| E. J. Smith, S. Schulze, S. Kiravittaya, Y. F. Mei, S. Sanchez, O. G. Schmidt Nano Lett. 11, 4037 (2011) URL PDF | ||
| Abstract | ||
We report a method for the precise capturing of embryonic fibroblast mouse cells into rolled-up microtube resonators. The microtubes contain a nanometer-sized gap in their wall which defines a new type of optofluidic sensor, i.e., a flexible split-wall microtube resonator sensor, employed as a label-free fully integrative detection tool for individual cells. The sensor action works through peak sharpening and spectral shifts of whispering gallery modes within the microresonators under light illumination. |