an array of rolled up nanomembranes


Microfluidics

4 Dec 2017

Chemotherapeutic micromotor for targeted drug delivery

A sperm-driven micromotor acts as a targeted drug delivery system to potentially treat diseases in the female reproductive tract. 

ACS Nano 12, 327 (2018)

24 May 2017

Opportunities and challenges of medical microbots

In this extended comment we call on microrobotics researchers, materials scientists, bioimaging and medical specialists to work together to tackle the challenges on the way to in-vivo applications.

Nature 545, 406 (2017)

21 Mar 2017

Spermatozoa as robotic microswimmers

V. Magdanz, M. Medina-Sánchez, L. Schwarz, H. Xu, J. Elgeti, O. G. Schmidt

Adv. Mater. 29, 1606301 (2017)

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24 Jan 2017

Monolithically integrated microtube cavities for optofluidic sensing

Monolithically integrated vertical ring resonators pave the way for optofluidics in three-dimensions on photonic chips.

Opt. Lett. 42, 486 (2017)

6 Jun 2016

High-performance DNA biosensor

Microtubular sensor reaches attomolar level detection of Avian Influenza Virus H1N1 DNA without any labelling or amplification. 

Nano Lett. 16, 4288 (2016)

6 Jun 2016

Human cancer cell mitosis in transparent microtubes

Tumor cell devision is mimicked inside blood capillaries by investigating single-cell mitosis of living human cancer cells trapped inside rolled-up microtubes. 

ACS Nano 10, 5835 (2016)

21 Dec 2015

Micromotorized sperms for artificial fertilization

Magnetically activated microhelices serve as motors for transporting sperm cells with motion deficiencies to help them carry out their natural function. 

Nano Lett. 16, 555 (2016)

30 Nov 2015

Biogenic microdaggers for single-cell surgery and drug release

S. K. Srivastava, M. Medina-Sánchez, B. Koch, O. G. Schmidt

Adv. Mater. 28, 832 (2016)

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	Efficient wastewater cleaning by self-propelled micromotors

Efficient wastewater cleaning by self-propelled micromotors

We present efficient wastewater-mediated activation of catalytic micromotors for the degradation of nitroaromatic pollutants in water.

Nano Lett. 16, 817 (2016)

	Neural stem cell migration under spatial confinement

Neural stem cell migration under spatial confinement

We exploit the well-defined geometry and optical transparency of glass microtubes to investigate how scaffold dimensionality and cell confinement influence the spontaneous migration of neural stem cells.

Nano Lett. 15, 5530 (2015)

	Rolled-up functionalized nanomembranes as three-dimensional cavities for single cell studies

Rolled-up functionalized nanomembranes as three-dimensional cavities for single cell studies

We use micropatterning and strain engineering to encapsulate single living mammalian cells into transparent tubular architectures consisting of 3D rolled-up nanomembranes.

Nano Lett., 14, 4197 (2014)

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	Impedemetric sensing of ionic fluids and single cells in a single microtube

Impedemetric sensing of ionic fluids and single cells in a single microtube

Ultracompact three-dimensional tubular structures integrating Au-based electrodes serve as impedimetric microsensors for the in-flow determination of mono- and divalent ionic species and HeLa cells. 

Nano Lett. 14, 2219 (2014)

	Flexible thermoresponsive microjets

Flexible thermoresponsive microjets

Flexible self-propelled microjets are formed by temperature-induced folding of thin polymer films into microtubes that contain an inner platinum layer for catalytic bubble propulsion in hydrogen peroxide.

Angew. Chem. Int. Ed. 53, 2673 (2014)

	A sperm driven micro-bio-robot

A sperm driven micro-bio-robot

V. Magdanz, S. Sanchez, O. G. Schmidt

Adv. Mater. 25, 6581 (2013)

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	Chemotactic behaviour of artificial engines

Chemotactic behaviour of artificial engines

Dr. L. Baraban, Dr. S. M. Harazim, Dr. S. Sanchez, Prof. Dr. O. G. Schmidt

Angew. Chem. Int. Edit. 52, 5552 (2013)

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	Rolled-up field effect transistors

Rolled-up field effect transistors

We fabricate inorganic thin film transistors with bending radii of less than 5μm maintaining their high electronic performance with on-off ratios of more than 100.000 and subthreshold swings of 160mV/dec.

Nano Lett. 13, 213 (2013)

	Elastic magnetic sensor with isotropic sensitivity for in-flow detection of magnetic objects

Elastic magnetic sensor with isotropic sensitivity for in-flow detection of magnetic objects

We present a conceptually new approach for the detection of magnetic objects flowing through a fluidic channel.

RSC Adv. 2, 2284 (2012)

	Self-propelled nanotools drilling into cells

Self-propelled nanotools drilling into cells

We design nanoscale tools in the form of autonomous and remotely guided catalytically self-propelled rolled-up tubes.

ACS Nano 6, 1751 (2012)

	Fabrication and applications of large arrays of multifunctional rolled-up SiO/SiO2 microtubes

Fabrication and applications of large arrays of multifunctional rolled-up SiO/SiO2 microtubes

S. M. Harazim, W. Xi, C. K. Schmidt, S. Sanchez, O. G. Schmidt

J. Mater. Chem. 22, 2878 (2012)

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	On-chip integration of rolled-up ring resonators as label-free optofluidic sensors

On-chip integration of rolled-up ring resonators as label-free optofluidic sensors

The advances we have made in engineering of tubular optical sensors and their on-chip integration allows us to fabricate rolled-up optofluidic ring resonators based on glass material with high quality factors fully integrated on-chip. 

Lab Chip 12, 2649 (2012)

	Lab-in-a-tube

Lab-in-a-tube

A lab-in-a-tube device comprises numerous ultracompact components in a single tube which can be developed using rolled-up technology.

Lab Chip 12, 1917 (2012)

	Lab-in-a-tube

Lab-in-a-tube for single cell optofluidic detection

E. J. Smith, S. Schulze, S. Kiravittaya, Y. Mei, S. Sanchez, O. G. Schmidt

Nano Lett. 11, 4037 (2011)

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	 Rolled-up magnetic sensor for in-flow detection of magnetic objects

Rolled-up magnetic sensor for in-flow detection of magnetic objects

Rolled-up nanotech is used to fabricate magnetic sensor devices, which are directly integrated into fluidic architectures.

ACS Nano 5, 7436 (2011)

	"Starting" and "stopping" microjet engines

"Starting" and "stopping" microjet engines

We report the tuning of the propulsion power of catalytic microjets through illumination of a solution by a white-light source.

Angew. Chem. Int. Edit. 50, 10875–10878 (2011)

	Superfast motion of catalytic microjet engines at physiological temperature

Superfast motion of catalytic microjet engines at physiological temperature

We fabricate microjet engines that acquire superfast speeds of 10 mm sec-1.

J. Am. Chem. Soc. 133, 14860 (2011)

	Towards remotely controlled intelligent microrobots

Towards remotely controlled intelligent microrobots

In this tutorial review we describe recent progress on catalytic microtubular engines fabricated by rolled-up nanotech.

Chem. Soc. Rev. 40, 2109 (2011)

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	Guinness World Record® for "Smallest Man-Made Jet Engine"

Guinness World Record® for "Smallest Man-Made Jet Engine"

"The smallest man-made jet engine measures just 600nm across and weighs 1 picogram.

Die Welt (March 8, 2011)

	Microbots swimming in the flowing streams of microfluidic channels

Microbots swimming in the flowing streams of microfluidic channels

The motion of artificial catalytic nanomachines is commonly studied in free bulk solution, which differs significantly from the stream-like channel networks existing in the human body. 

J. Am. Chem. Soc. 133, 701 (2011)

	Transport of animal cell material by catalytic microbots

Transport of animal cell material by catalytic microbots

Animal cells can be transported within a fluid in a controllable manner by using artificial microbots.

Chem. Commun. 47, 698-700 (2011)

	Tubular optofluidic sensors for enhanced refractive index sensing

Tubular optofluidic sensors for enhanced refractive index sensing

Optofluidic microcavities from rolled-up ring resonators with subwavelength wall thicknesses are fabricated with excellent sensing function.

ACS Nano 4, 3123 (2010)

	Neuron cells cultured in rolled-up microtubes

Neuron cells cultured in rolled-up microtubes

Primary mouse motor neurons and immortalised CAD cells, a cell line derived from the central nervous system, can be well cultured on arrays of rolled-up microtubes.

Adv. Eng. Mater. 12, B558 (2010)

	Collective behaviour of artifcial autonomous systems

Collective behaviour of artifcial autonomous systems

Artificial autonomous systems act as catalytic water striders at the air–liquid interface of hydrogen peroxide solution.

Adv. Mater. 22, 4340 (2010)

	Highly efficient locomotion of hybrid biocatalytic microengines

Highly efficient locomotion of hybrid biocatalytic microengines

We have designed a novel hybrid biocatalytic microengine.

J. Am. Chem. Soc. 132, 13144 (2010)

	Magnetic control of tubular catalytic microbots

Magnetic control of tubular catalytic microbots

A. A. Solovev, S. Sanchez, M. Pumera, Y. F. Mei, O. G. Schmidt

Adv. Funct. Mater. 20, 2430 (2010)

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	 Cell culturing in single tubes integrated on a Si Chip

Cell culturing in single tubes integrated on a Si Chip

Detailed investigations of individual yeast cells in a single transparent microtube reveal the mechanical interaction between the tube and the 2D confined cells causing different cellular assemblies. 

Lab Chip 9, 263-268 (2009)

	Microtubular jet engines

Microtubular jet engines

A. A. Solovev, Y. Mei, E. B. Ureña, G. Huang, O. G. Schmidt

Small 5, 1688 (2009)

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	Ferngesteuerte Mikroraketen

Ferngesteuerte Mikroraketen

Wir haben winzige Mikroraketen hergestellt, die sich durch ein Magnetfeld fernsteuern lassen.

Spektrum der Wissenschaft, S.16, Juli 2009

Welt der Physik 16.05.2009

	Strain engineered micro-/nanotubes on polymers

Strain engineered micro-/nanotubes on polymers

Y. Mei, G. Huang, A. A. Solovev, E. Bermúdez Ureña, I. Mönch, F. Ding, T. Reindl, R. K. Y. Fu, P. K. Chu, O. G. Schmidt

Adv. Mater. 20, 4085 (2008)

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	Self-organisation into nanochannel networks

Self-organisation of nanochannel networks

A. Malachias, Y. Mei, R. K. Annabattula, C. Deneke, P. R. Onck, O. G. Schmidt

ACS Nano 2: 1715 (2008)

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	Glucose detection on the femtoliter scale

Glucose detection on the femtoliter scale

We use Si/SiO microtubes as optofluidic components to sense glucose concentrations in water. 

Appl. Phys. Lett. 93, 094106 (2008)

	Nanochannel arrays by deterministic layer wrinkling

Nanochannel arrays by deterministic layer wrinkling

We have developed a method that exploits the deterministic wrinkling and a subsequent bond-back of a semiconductor layer to create well-defined and versatile nanochannel networks.

Adv. Mater. 19, 2124 (2007)